Evaluation of serum zinc levels in hospitalized children with bacterial pneumonia in Shahid Motahari Hospital
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Abstract:
Introduction: Pneumonia in children is the cause of approximately 30% of deaths in the world. The role of zinc as an important micronutrient in the treatment of pneumonia is still unclear. This substance has the properties of improving the function of the immune system, and its deficiency is associated with an increase in the risk of infectious diseases, as well as impaired growth and development. Therefore, the present study was designed and implemented with the aim of determining the serum level of zinc in children hospitalized with pneumonia in Shahid Motahari Hospital and comparing it with children without pneumonia.
Materials and Methods: A case-control study was conducted on 100 patients between the ages of 1 and 59 months between January 2022 and July 2022, 50 children admitted to Urmia Motahari Hospital in Iran with a diagnosis of pneumonia based on WHO criteria as a group The case and 50 other children were studied as a control group among the patients referred to the children's infectious superspecialty clinic. Zinc level was measured in two groups. The data was entered into SPSS software and subjected to statistical analysis.
Results: The average level of zinc in the case group was 67.35 ± 42.03 and in the control group it was 93.26 ± 41.80. According to the results of the independent t-test, the level of zinc in the control group was significantly higher (p=0.003). The results of the study showed that the level of zinc in hospitalization for more than 10 days was significantly lower than in hospitalization for less than 10 days (1-5 and 6-10 days). Also, the average serum zinc level was lower in patients with complications and this difference was statistically significant in empyema (P=0.02), pleural effusion (P=0.02) and ventilation (P=0.01). The average serum zinc level in patients with wheezing (P=0.02), stridor (P=0.04), cyanosis (P=0.001), sleep disorder (P=0.001) and lethargy (0.04) =P) was significantly less.
Conclusion: The average level of zinc in children with pneumonia was significantly lower than the control group.
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